NeuGen is made for generation of dendritic and axonal morphology of realistic neurons and networks in 3DThe idea for the development of NeuGen has been to be able to simulate networks of synaptically connected neurons in a cortical column. The NeuGen project is mainly a result of the fact that experimental data is available nowadays to extract the anatomical fingerprints of the cells and to generate synthetic neuron geometries.
NeuGen generates nonidentical neurons of morphological classes of the cortex, e.g., pyramidal cells and stellate neurons, and synaptically connected neural networks in 3D. It is based on sets of descriptive and iterative rules which represent the axonal and dendritic geometry of neurons by inter-correlating morphological parameters. The generation algorithm stochastically samples parameter values from distribution functions induced by experimental data. The generator is adequate for the geometric modelling and for the construction of the morphology.
The generated neurons can be exported into a 3D graphic format for visualization and into multi-compartment files for simulations with the program NEURON. NeuGen is intended for scientists aiming at simulations of realistic networks in 3D.